Cécile is enjoying her older brother Armand's return from France and her growing friendship with Marie-Grace, with whom she volunteers at an orphanage, until the yellow fever epidemic theatening New Orleans strikes her own household.
As the yellow fever epidemic continues to ravage New Orleans and the orphanages become more crowded, Marie-Grace and Cécile help with the orphans, until Marie-Grace learns that her Uncle Luc's fiancée, Mademoiselle Océane, has fallen ill.